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Reversal of Neuromuscular Blockade clinical trials at UC Davis
1 research study open to eligible people

  • A Study of the Safety of Experimental Sugammadex to Help Muscles Recover After Surgery in Patients With Severe Disease

    “If you are undergoing general anesthesia, Sugammadex or neostigmine can be used to reverse muscle relaxation.”

    open to eligible people ages 18 years and up

    This is a randomized, active comparator-controlled, parallel-group, multi-site, double-blind safety trial of sugammadex (MK-8616) for the reversal of neuromuscular blockade (NMB) induced by rocuronium or vecuronium in adult ASA Physical Status Class 3 and 4 participants. The first primary objective of this study is to characterize the incidence of treatment emergent sinus bradycardia, treatment emergent sinus tachycardia, or other treatment emergent cardiac arrhythmias after administration of sugammadex. The second primary objective of this study is to evaluate the general safety of sugammadex in a population of ASA Class 3 and 4 subjects in a surgical setting.

    Sacramento, California and other locations

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