Summary

for people ages 18 years and up (full criteria)
at Sacramento, California
study started
estimated completion
Neal Fleming, MD, PhD

Description

Summary

This is a prospective, randomized, sequential data collection study to evaluate the ability of pleth variability index (PVI) to predict fluid responsiveness in comparison with other dynamic parameters including pulse pressure variation (PPV) and stroke volume variation (SVV).

Official Title

Validation of PVI as a Parameter to Predict Fluid Responsiveness

Details

Patients will be randomized to a tidal volume of either 6 or 8 ml.kg-1 of ideal body weight, with positive end-expiratory pressure set between 3 and 5 cmH20.

The finger sensor will be applied to patients in the OR, and hemodynamic measurements will be collected from standard OR monitors.

Keywords

Surgery PVI Dynamic Cardiac Monitors SVV PPV Masimo Rainbow sensor

Eligibility

You can join if…

Open to people ages 18 years and up

  • 18 years of age or older
  • Scheduled for elective surgery requiring general anesthesia and mechanical ventilation
  • Arterial line and Swan-Ganz catheter placed as part of the scheduled surgical procedure

You CAN'T join if...

  • Patients with surgeries at or around site of sensor placement
  • Skin abnormalities affecting the sensor placement area
  • Patients with cardiac arrhythmias
  • Patients with intracardiac shunts

Location

  • UC Davis Health accepting new patients
    Sacramento California 95817 United States

Lead Scientist

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Davis
Links
Changes in Arterial Pressure during Mechanical Ventilation
Assessment of Trending Ability of Cardiac Output Monitors by Polar Plot Methodology
Sign up for this study
ID
NCT03075150
Study Type
Observational
Last Updated