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Duchenne Muscular Dystrophy clinical trials at UC Davis

5 research studies open to eligible people

Showing trials for
  • A Research Study of Pamrevlumab or Placebo with Steroids in Duchenne Muscular Dystrophy (DMD)

    open to eligible males ages 12 years and up

    To evaluate the efficacy and safety of pamrevlumab versus placebo in combination with systemic corticosteroids in subjects with non-ambulatory Duchenne muscular dystrophy (age 12 years and older).

    Sacramento, California and other locations

  • A Study of Experimental ASP0367 in Pediatric Male Patients with Duchenne Muscular Dystrophy

    open to eligible males ages 8-16

    The primary purpose of this study is to evaluate the safety and tolerability of ASP0367. This study will also evaluate the pharmacokinetics, pharmacodynamics and efficacy on muscle function of ASP0367.

    Sacramento, California and other locations

  • A Study of Experimental Ataluren for Nonsense Mutation Dystrophinopathy (nmDBMD)

    open to eligible males

    The objective of this study is to assess the safety and tolerability of 10, 10, 20 milligrams per kilogram (mg/kg) ataluren in participants with nmDBMD who had prior exposure to ataluren in a PTC sponsored clinical trial or treatment plan. The treatment will continue under this protocol until consent withdrawal by participants, withdrawal due to worsen condition after initiating ataluren treatment, withdrawal by investigator, withdrawal due to participant unable to tolerate ataluren, participant is eligible to participate in another ataluren nmDBMD clinical trial program initiated by sponsor, study is discontinued by the relevant regulatory authority and/or sponsor, or until ataluren becomes commercially available.

    Sacramento, California and other locations

  • Expanded Access to Experimental Vamorolone for Boys With Duchenne Muscular Dystrophy

    open to eligible males

    The intent of this protocol is to provide continued access to vamorolone for subjects in the United States who Have Completed the VBP15-LTE or VBP15- 004 protocols (and are thereby ineligible to enroll in another trial of vamorolone therapy), during the time a new drug application for vamorolone is under preparation and review

    Davis, California and other locations

  • Study to Test the Effectiveness and Safety of Experimental Viltolarsen in Ambulant Boys With Duchenne Muscular Dystrophy (DMD)

    open to eligible males ages 4-7

    The main objective of this study is to evaluate the efficacy of Viltolarsen compared to placebo in Duchenne muscular dystrophy (DMD) patients amenable to exon 53 skipping.

    Sacramento, California and other locations

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