Clinical Trials Open to Healthy Volunteers

A “healthy volunteer” is someone who doesn't have any major health problems, and takes part in research to test new medicines, devices, or treatments. UC Davis offers clinical trials on a wide range of medical conditions. Healthy volunteers can help UC Davis researchers make better comparisons to better understand the treatment of diseases.

• A Registry Study Called the International Pleuropulmonary Blastoma Registry for PPB, DICER1, and Associated Conditions

  “This Registry Study is for individuals that have a condition which may be associated with a gene called DICER1.”

  • study on Pleuropulmonary Blastoma and Sertoli-Leydig Cell Tumor
  • open to healthy people

• A study following patients with Huntington's Disease over time

  “Help us learn more about Huntington's Disease”

  • study on Huntington's Disease
  • open to healthy people ages 18 years and up

• A Study of Olive Oil Polyphenols (molecules in plant-based food) and Cardiovascular Health

  • study on Normal Weight and Obesity
  • open to healthy people ages 20-45

• A Study of Opioid Use in Shoulder Arthroplasty Patients

  • study on Opioid Use
  • open to healthy people ages 18 years and up

• A Study of Satisfaction With School-Based Telemedicine

  “This is a research study to determine parent/guardian satisfaction with care.”

  • study on Physical and Rehabilitation Medicine and Physical Therapy Modalities
  • open to healthy people ages up to 21 years

• A Study of Senicapoc in Alzheimer’s Disease

  “Volunteer for research and contribute to discoveries that may improve health care for you, your family, and your community!”

  • study on Mild Cognitive Impairment and Alzheimer's Disease
  • open to healthy people ages 55-85

• A Study of the Effect of Orange Juice or Sugar-Sweetened Beverages on Risk Factors for Type 2 Diabetes and Cardiovascular Disease

  “In this study, the study team will provide meals and either sugar-sweetened beverages or orange juice.”

  • study on Cardiovascular Disease and Diabetes
  • open to healthy people ages 18-50

• A Study of the Effects of Brain Stimulation on Higher-Order Cognition

  • study on Schizophrenia and Transcranial Direct Current Stimulation
  • open to healthy people ages 18-35

• A Study of the Effects of Sweet Cherry Juice on Metabolism (converting food to energy) and Heart Health

  • study on Obesity and Metabolic Syndrome
  • open to healthy people ages 20-65

• A Study of the Experimental Medicine Ropivacaine for Pain Control After Kidney Transplant

  • study on Postoperative Pain and Kidney Transplant
  • open to healthy people ages 18 years and up

• A Study of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) in Kids

  • study on Oxygen Deficiency and Desaturation of Blood
  • open to healthy people ages up to 18 years

• An Evaluation of the Health Education Theater Course

  • study on Health Education
  • open to healthy people ages 18 years and up

• Are you a healthy adult? Join a study to help us learn more about the role of pulses in a healthy diet!

  “Volunteer for research and contribute to discoveries that may improve health care for you, your family, and your community!”

  • open to healthy people ages 18-65

• Are you a man between 60 and 80 years old? Help us learn about how strawberries influence your health!

  “We are inviting older men to participate in a study about the vascular health effects of strawberries.”

  • study on Vascular Dilation
  • open to healthy males ages 60-80

• Are you pregnant? Participate in a vaccine study trying to protect babies from Respiratory Syncytial Virus!

  “Pass on what's important: You’ll give them love in lots of ways. Could protection from RSV be one of them?”

  • study on Respiratory Tract Infection and RSV
  • open to healthy females ages 0-49

• Cardiovascular Effects of Prenatal Methamphetamine Exposure

  • study on Methamphetamines
  • open to healthy people

• Child to Adult Neurodevelopment in Gene Expanded Huntington’s Disease

  • study on Huntington's Disease
  • open to healthy people ages 6-30

• Determining how melanoma interacts with the immune system

  “A study of the immune systems interaction with melanoma”

  • study on Skin Cancer/Melanoma
  • open to healthy people ages 18-85

• Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc

  “Volunteer for research and contribute to discoveries that may improve health care for you, your family, and your community!”

  • study on Zinc Deficiency and Inflammation
  • open to healthy people ages 55-70

• Effects of tDCS on Cognition and Brain Chemistry

  “Volunteer for paid research and contribute to discoveries that may improve health care for you, your family, and your community!”

  • study on Schizophrenia and Transcranial Direct Current Stimulation
  • open to healthy people ages 18-35

• The Effects of Transcranial Direct Current Stimulation (tDCS) on the Neuronal Mechanisms of Cognitive Control in Schizophrenia

  “Help us develop new treatments for patients who have difficulty with brain functions such as reasoning, including schizophrenic patients”

  • study on Schizophrenia and Transcranial Direct Current Stimulation
  • open to healthy people ages 18-35

• Evaluating Assessment and Medication Treatment of ADHD in Children With Down Syndrome

  • study on Down Syndrome and Attention-Deficit/Hyperactivity Disorder
  • open to healthy people ages 6-17

• Healthy pregnancy study

  “We're looking for healthy pregnant people to participate in a mobile health program”

  • study on Pregnancy and Gestational Weight Gain
  • open to healthy females ages 18-44

• Join this nutrition study of the influence of honey-flavored yogurt on gut health!

  “We are inviting women to participate in a research study to test the health benefits of honey-flavored yogurt!”

  • study on Obesity
  • open to healthy females ages 45-65

• Metabolic and Bio-Behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans (DGA4ME) Study

  • study on Obesity
  • open to healthy females ages 35-64

• New COVID-19 Research Opportunity for Previously Vaccinated, Healthy Adults Aged 18 or Older

  “Volunteer for research and contribute to discoveries that may improve health care for you, your family, and your community!”

  • study on COVID-19
  • open to healthy people ages 12 years and up

• Radiofrequency Ablation (heat therapy to reduce nerve pain) For Vertebral Compression Fracture Pain

  • study on Vertebral Compression Fracture and Facet Joint Pain
  • open to healthy people ages 18-90

• Study of monoclonal antibodies for household members of patients with COVID-19

  “We're looking for household contacts of someone with COVID-19 to see if a new medicine may prevent infection or reduce severity of COVID-19”

  • study on COVID-19
  • open to healthy people

• Study to Assess the Effectiveness and Safety of Lenacapavir for Human Immunodeficiency Virus (HIV) Pre-Exposure Prophylaxis

  “Volunteer for research and contribute to discoveries that may improve health care for you, your family, and your community!”

  • study on HIV/AIDS and PrEP
  • open to healthy people ages 16 years and up

• Study to examine if video self review of intubation skills by medical students help them learn the skill faster

  “Video of medical students performing intubation on patients to aid in their education and competency of this skill”

  • study on Surgery
  • open to healthy people

• Taking a birth control pill or planning to? Willing to use a birth control implant too?

  “Join a study that aims to improve how well your birth control works at preventing pregnancy!”

  • study on Contraception
  • open to healthy females ages 18 years and up

• Using Kinect Motion Capture to Measure Shoulder Motion for Capsular Distension in Adhesive Capsulitis (frozen shoulder)

  • study on Adhesive Capsulitis and Adhesive Capsulitis of Shoulder
  • open to healthy people ages 18 years and up

• Viral Therapy in High Risk Early Melanoma

  • study on Skin Cancer/Melanoma
  • open to healthy people ages 18 years and up

• Walnut Study

  “Postmenopausal Women Needed for a Research Study”

  • study on Obesity and Weight Management
  • open to healthy females ages 45-65

• WHNRC Fiber Intervention Study

  • study on Inflammation and Vaccine
  • open to healthy people ages 18-50

• The WISDOM Study (thewisdomstudy.org)

  “What is the best mammogram screening schedule for women? Clinical experts disagree. Help us find out!”

  • study on Breast Cancer
  • open to healthy females ages 40-74