Pleuropulmonary Blastoma clinical trials at UC Davis
1 research study open to eligible people
A Registry Study Called the International Pleuropulmonary Blastoma Registry for PPB, DICER1, and Associated Conditions
“This Registry Study is for individuals that have a condition which may be associated with a gene called DICER1.”
open to all eligible people
Pleuropulmonary blastoma (PPB) is a rare malignant neoplasm of the lung presenting in early childhood. Type I PPB is a purely cystic lesion, Type II is a partially cystic, partially solid tumor, Type III is a completely solid tumor. Treatment of children with PPB is at the discretion of the treating institution. This study builds off of the 2009 study and will also seek to enroll individuals with DICER1-associated conditions, some of whom may present only with the DICER1 gene mutation, which will help the Registry understand how these tumors and conditions develop, their clinical course and the most effective treatments.