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Respiratory Distress Syndrome clinical trials at UC Davis

3 research studies open to eligible people

Showing trials for
  • Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome

    “The study team wants to know if adding a sigh-type of breath to a ventilator reduces chances of developing more serious lung problems.”

    open to eligible people ages 18-89

    A randomized, concurrent controlled trial to assess if adding sigh breaths to usual invasive mechanical ventilation of victims of trauma who are at risk of developing ARDS will decrease the number of days they require invasive mechanical ventilation.

    Sacramento, California and other locations

  • Study of Higher breathing machine pressure settings with/without muscle relaxant for Acute Respiratory Distress Syndrome (ARDS)

    “Does early treatment with muscle relaxant improve recovery from lung injury?”

    open to eligible people ages 18 years and up

    This study evaluates whether giving a neuromuscular blocker (skeletal muscle relaxant) to a patient with acute respiratory distress syndrome will improve survival. Half of the patients will receive a neuromuscular blocker for two days and in the other half the use of neuromuscular blockers will be discouraged.

    Sacramento, California and other locations

  • The PROSpect Study: A Pediatric Study to Test the Best Breathing Position for Children When They Are Sick

    open to eligible people ages up to 18 years

    Severe pediatric acute respiratory distress syndrome (PARDS) is a life-threatening and frequent problem experienced by thousands of children each year. Little evidence supports current supportive practices during their critical illness. The overall objective of this study is to identify the best positional and/or ventilation practice that leads to improved patient outcomes in these critically ill children. We hypothesize that children with severe PARDS treated with either prone positioning or high-frequency oscillatory ventilation (HFOV) will demonstrate more days off the ventilator when compared to children treated with supine positioning or conventional mechanical ventilation (CMV).

    Sacramento, California and other locations

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