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Stroke clinical trials at UC Davis

4 research studies open to eligible people

Showing trials for
  • A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel

    “Volunteer for research and contribute to discoveries that may improve health care for you, your family, and your community!”

    open to eligible people ages 40 years and up

    The purpose of this clinical study is to determine whether the addition of an oral Factor XIa Inhibitor to Aspirin and Clopidogrel is more effective than standard therapy in secondary stroke prevention.

    Sacramento, California and other locations

  • Blood Markers of Stroke and Brain Hemorrhage

    “This study hopes to learn whether there are changes in the genetic material of people who have had a stroke or brain hemorrhage”

    open to eligible people ages 18 years and up

    This study will evaluate whether a gene marker can improve the identification of atrial fibrillation in patients with ischemic stroke, and evaluate whether the decision to anticoagulate could be improved by a marker of atrial fibrillation.

    Sacramento, California

  • Effectiveness and Safety of Experimental BIIB093 (Glibenclamide) for Severe Cerebral Edema (fluid around brain) After Stroke

    open to eligible people ages 18-85

    The primary objective of Part 1 of the study is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives of Part 1 of the study are to determine if BIIB093 improves overall survival at Day 90 when compared with placebo, if BIIB093 improves functional outcome at Day 90 on the mRS dichotomized 0-4 vs. 5-6 when compared with placebo, if BIIB093 reduces midline shift at 72 hours (or at time of decompressive craniectomy [DC] or comfort measures only [CMO], if earlier) when compared with placebo, and to evaluate the safety and tolerability of BIIB093 in participants with LHI. The objectives of Part 2 of the study are to evaluate long-term disability following LHI, to evaluate long-term outcome measures of clinical function, quality of life, and healthcare utilization, and to assess the safety of BIIB093 in subjects with LHI during the follow-up period.

    Sacramento, California and other locations

  • Stroke Protection With Sentinel During Transcatheter Aortic Valve Replacement

    open to all eligible people

    To demonstrate that use of the Sentinel® Cerebral Protection System significantly reduces the risk of peri-procedural stroke (≤72 hours) after transcatheter aortic valve replacement (TAVR).

    Sacramento, California and other locations