Trinucleotide Repeat Expansion clinical trials at UC Davis
1 research study open to eligible people
A Study of Experimental Treatment With Metformin for Fragile X Syndrome
“Learn if Metformin may be helpful for language, behavior problems, and obesity / excessive appetite in patients with Fragile X Syndrome.”
open to eligible people ages 6-25
This study is a controlled trial of metformin in individuals with fragile X syndrome between the ages of 6 and 25 years. Participants will be randomized in a double-blind design to either drug or placebo and will attend three visits to the study site in a 4-month period for a series of tests. The primary objectives are to assess safety, tolerability, and efficacy of metformin in the treatment of language deficits, behavior problems, and obesity/excessive appetite in individuals with fragile X syndrome.
Our lead scientists for Trinucleotide Repeat Expansion research studies include Randi J Hagerman, MD.