Chronic Myelomonocytic Leukemia clinical trials at UC Davis
3 research studies open to eligible people
CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML
open to eligible people ages 18 years and up
The purpose of this study is to test the safety of an investigational drug called CFI-400945 alone and in combination with azacitidine.
Sacramento, California and other locations
IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML
open to eligible people ages 18 years and up
To assess safety and tolerability at increasing dose levels of IO-202 in successive cohorts of participants with AML with monocytic differentiation and CMML in order to estimate the maximum tolerated dose (MTD) or maximum administered dose (MAD) and select the recommended Phase 2 dose (RP2D)
Davis, California and other locations
Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations
open to eligible people ages 18 years and up
This is an open-label, multi-center Phase 1 study of LY3410738, an oral, covalent isocitrate dehydrogenase (IDH) inhibitor, in patients with IDH1 and/or IDH2-mutant advanced hematologic malignancies who may have received standard therapy
Sacramento, California and other locations