Chronic Obstructive Pulmonary Disease clinical trials at UC Davis

4 in progress, 1 open to eligible people

Showing trials for

  • Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

    “Volunteer for research and contribute to discoveries that may improve health care for you, your family, and your community!”

    open to eligible people ages 40-84

    The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphysema suffering from dyspnea due to hyperinflation despite optimal medical treatment. The Apreo BREATHE Airway Scaffold is a permanent implant designed to tent open native airways. The study will include up to 250 participants at up to 25 study centers located in the United States and Europe. Study subjects will be followed for 3 years. The main questions it aims to answer are: Is it safe? Does it work?

    Sacramento, California and other locations

  • Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema

    “Alpha 1 Antitrypsin Deficiency Infusion Trial”

    Sorry, in progress, not accepting new patients

    Phase 2 open label extension study to evaluate SAR447537 (INBRX-101) in adults with AATD emphysema

    Sacramento, California and other locations

  • TLD in Patients with COPD

    Sorry, in progress, not accepting new patients

    The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System (Nuvaira System) in the treatment of COPD.

    Sacramento, California and other locations

  • RejuvenAir® System Trial for COPD With Chronic Bronchitis

    Sorry, in progress, not accepting new patients

    Chronic Obstructive Pulmonary Disease (COPD) is defined as an impaired ability to move air within the lungs and is a major public health problem that is projected to rank fifth worldwide in terms of disease burden and third in terms of mortality. Chronic bronchitis (CB) is a common clinical phenotype within the umbrella of a COPD diagnosis and is classically defined as chronic cough and sputum production for 3 months a year for 2 consecutive years2, but many studies have used different definitions to define it- chronic cough and sputum production for one year or cough and sputum production on most days of the week. CB is associated with multiple clinical consequences, including; the worsening of lung function decline, increasing risk of acute exacerbations of COPD, increased risk of developing pneumonia, reduced health related quality of life, and an increase in all-cause mortality.

    Sacramento, California and other locations

Our lead scientists for Chronic Obstructive Pulmonary Disease research studies include .

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