Summary

for people ages 18 years and up (full criteria)
at Sacramento, California
study started
estimated completion

Description

Summary

The objective of this protocol is to further elucidate the genetic mutations that drive melanocytic nevi (benign melanocytic neoplasms, moles). This will be performed by whole genome, whole exome, or targeted sequencing of de-identified specimens. Herein, the investigators plan to isolate DNA from de-identified skin biopsy specimens and blood samples: 1. From melanocytic nevi collected by skin biopsy (a shave or punch biopsy). A part of the tissue will be submitted for routine diagnostic dermatopathology and investigational histomorphologic and immunohistochemical analysis. 2. From corresponding normal tissue (blood). DNA isolated from blood will be used as a normal control when analyzing sequencing data to identify somatic mutations in lesional tissue.

Official Title

Genetic Basis of Melanocytic Nevi

Keywords

Melanocytic Nevi Nevus Nevus, Pigmented Nevus, Epithelioid and Spindle Cell Collecting Nevi

Eligibility

You can join if…

Open to people ages 18 years and up

  • Male or female subjects that are 18 years or older
  • Subjects with melanocytic nevi\

You CAN'T join if...

  • Patients less than 18 years of age
  • Patients without melanocytic nevi
  • Patients with a bleeding disorder or are taking anticoagulation medication

Location

  • University of California-Davis, Department of Dermatology accepting new patients
    Sacramento California 95816 United States

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Davis
Links
Sign up for this study
ID
NCT03054584
Study Type
Observational
Last Updated