for people ages 18 years and up (full criteria)
at Sacramento, California
study started
estimated completion



Investigator initiated prospective study to determine whether use of Continuous Positive Airway Pressure (CPAP) can improve the swallow function in patients who underwent total laryngectomy and are experiencing difficulty swallowing

Official Title

Utilization of Continuous Positive Airway Pressure to Improve Swallow Function in Patients Post Total Laryngectomy


Total laryngectomy is a procedure that involves surgical removal of the larynx and separation of the digestive and airway tracts. The procedure is typically conducted for cases of laryngeal cancer and intractable aspiration. Following this procedure, patients are no longer at risk for aspiration; however some patients continue to experience difficulties in propulsion of food or drink throughout the pharynx. Previous research has demonstrated a reduction in pharyngeal contractile pressure and increased pharyngeal transit time in patients post laryngectomy. Continuous Positive Airway Pressure (CPAP) may assist bolus propulsion in these patients by increasing pressure in the direction of bolus flow. This study aims to evaluate the utility of a CPAP mask to improve pharyngeal swallow outcomes during Video Fluoroscopic Swallowing Exam (VFSE) in patients with dysphagia following total laryngectomy. This specific population could be well-suited for this application, since the digestive tract and airway are completely separate and there is no risk of the aspiration into the airway.


Oropharyngeal Dysphagia Laryngectomy; Status Dysphagia Total Laryngectomy Video Fluoroscopic Swallowing Exam (VFSE) Deglutition Disorders Continuous Positive Airway Pressure Continue Positive Airway Pressure


You can join if…

Open to people ages 18 years and up

  • Patients at least 2 months after total laryngectomy
  • Undergoing Video Fluoroscopic Swallowing Examination

You CAN'T join if...

  • Patients with 100% neopharyngeal stenosis
  • Patients with active cancer within 2 months of the study
  • Patients with pharyngocutaneous fistula
  • Vulnerable population: Adults unable to consent, Pregnant women, and Prisoners


  • UC Davis Medical Center accepting new patients
    Sacramento California 95817 United States


accepting new patients
Start Date
Completion Date
University of California, Davis
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