Summary

for people ages 18 years and up (full criteria)
at Sacramento, California
study started
estimated completion

Description

Summary

This is an investigator initiated prospective study to determine whether the use of a negative pressure suction in the hypopharynx will reduce the amount of aspiration during Video Fluoroscopic Swallowing Exam (VFSE) among patients with oropharyngeal dysphagia.

Official Title

Utilization of Negative Pressure Suction to Reduce Aspiration in Oropharyngeal Dysphagia

Details

During a properly coordinated swallow, the oropharynx, larynx, and hypopharynx undergo a series of movements that serve to prepare and expand the pharyngoesophageal segment (PES), which is the inlet into the esophagus. Under normal circumstances, a food bolus is safely propelled from the oropharynx, through the PES, and into the esophagus. Surgical and radiation therapy in the head and neck, as well as deficiencies such as poor coordination, mistiming, or obstructing lesions may prevent the food bolus from safely entering the esophagus and instead diverting toward the trachea.

A number of patients with severe oropharyngeal dysphagia are not able to tolerate any diet without risking aspiration and subsequent pneumonia, often to a degree severe enough that they cannot manage to safely swallow their secreted saliva. These patients depend on a gastrostomy feeding tube in order to obtain adequate daily nutritional requirements and must suction or spit out their saliva to prevent aspiration and a sensation of asphyxiation. Despite these precautions, many of these patients ultimately suffer life-threatening pneumonia. Investigators will be testing if the use of use of a negative pressure suction in the hypopharynx will reduce the amount of aspiration during Video Fluoroscopic Swallowing Exam (VFSE) among patients with severe oropharyngeal dysphagia

Keywords

Oropharyngeal Dysphagia Dysphagia Video Fluoroscopic Swallowing Exam (VFSE) Deglutition Disorders Negative Pressure Suction Catheter Negative Pressure Suction Device

Eligibility

You can join if…

Open to people ages 18 years and up

  • Patients with videofluoroscopic evidence of aspiration with Rosenbek Penetration Aspiration Scale (PAS) greater than 5 for all tested food consistencies
  • Gastrostomy tube dependence
  • Exhaustion of conventional treatment options (physical, medical, and surgical therapies)

You CAN'T join if...

  • Complete PES stricture
  • Inability to follow commands
  • Current malignant disease
  • No gastrostomy tube present
  • Less than two years of cancer-free survival (if applicable)
  • Vulnerable populations: adults unable to consent, pregnant women, and prisoners

Location

  • UC Davis Medical Center
    Sacramento California 95817 United States

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Davis
Links
Sign up for this study
ID
NCT03368079
Study Type
Interventional
Last Updated